Appendix for Lorrca® MaxSis
Lorrca Maxsis User Manual Page 197
Version 5.04 MRN-231-EN
11.6.1. Preface
The Laser-assisted Optical Rotational Cell Analyzer (LORCA) was developed at the Academic
Medical Center (AMC) in Amsterdam by Dr. M.R.Hardeman and P.T.Goedhart and has been used
for many years at the Laboratory for Clinical Hemorheology at the Dept. of Internal Medicine
Reference 26
1
, 31
2
.
Later models where enhanced and the instrument was extended for aggregation measurements.
The software packages and documentation were implemented by Dr. J.G.G. Dobbe from the Dept.
of Medical Technological Development. 15,16 The instrument was made commercially available by
R&R Mechatronics38 up to 2008 under the name LoRRca.
In 2009 the original hardware was improved and extended with the facility to measure red cell
deformability under a gradient of medium osmolalities (REF). The corresponding new software was
written by Mechatronics Instruments B.V. The new version of this instrument is named: LoRRca
MaxSis.
1
Hardeman M.R., De Rie M.A., Schut N.H., Wilmink J.H., Impaired erythrocyte deformability in psoriasis
patients after treatment with cyclosporin, Clin. Hemorheol., vol. 11:(6), pp. 784, 1991.
2
Hardeman M.R., Goedhart P.T., Dobbe J.G.G., Lettinga K.P., Laser-assisted Optical Rotational Cell
Analyser (LORCA); A new instrument for measurement of various structural hemorheological parameters,
Clin. Hemorheol., vol. 14:(4), pp. 605-618, 1994.
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