Roche cobas b 123 - Page 100

Roche Diagnostics
100 Instructions for Use · Version 13.0
4 Theoretical foundations cobas b 123 POC system
Parameters and calculations
Unit: [%]
[3][4]
Equation 4-11
where
Equation 4-12
Adult
[3]
P
50
= 26.7
o F1 = 1.661
o F2 = 0.074
o F3 = 4.172
Fetal
[3]
P
50
= 21.5
o F1 = 1.3632
o F2 = 0.0533
o F3 = 4.113
P
50
The PO
2
value at which 50% of the hemoglobin is saturated with oxygen. P
50
can only
be calculated if measured SO
2
is available.
Unit: [mmHg]
Equation 4-13
where
Equation 4-14
Adult
[3]
F3 = 4.172
Fetal
[3]
F3 = 4.113
100
1+Q
Q
BE) a/f, 50, pH, ,O(O)(
2
2
⋅== PPScSO
BE0.0013+)
26.7
50
lg(-7.4)-(pH0.48OlgOlg
3F101FOlg 2.9=lgQ
2
k
2
O2F
k
2
k
2
⋅⋅+=
−⋅+⋅
⋅−
P
PP
P
P
()
k
22
OlgOlg
107.2650
PP
P
−
⋅=
2
2
k
2
O%100
O
Q
9.2
)F3Q(lg
Olg
S
S
−
=
+
=P