Roche cobas b 123 - Substances Without Effect on Thb, so, Hb Derivatives and Bilirubin

Roche Diagnostics
Instructions for Use · Version 13.0 147
cobas b 123 POC system 6 Measurement
Interferences
Substances without effect on tHb, SO
2
, Hb derivatives and bilirubin
Sodium chloride
(1)
45 mmol/L BG, pH, ISE, Glu, Lac
Sodium fluoride
(1)
0.105 mmol/L BG, pH, ISE, Glu, Lac
Sodium glutamate 0.86 mmol/L ISE, Glu, Lac
Sodium heparin
(1)
3000 IU/L BG, ISE, Glu, Lac
Sodium hydrogen carbonate
(sodium bicarbonate)
(1)
35 mmol/L ISE, Glu, Lac
Sodium iodide 2.99 mmol/L
BG, pH, K
+
, Ca
2+
, Glu, Lac
Sodium nitroprusside 4.00 mmol/L
pH, K
+
, Ca
2+
, Glu, Lac
Sodium perchlorate 1.50 mmol/L
K
+
, Glu, Lac
Sodium pyruvate
(1)
0.309 mmol/L BG, pH, ISE, Glu, Lac
Theophylline
(1)
0.222 mmol/L ISE, Glu, Lac
Thiopental (Trapanal)
(1)
0.248 mmol/L pH, ISE, Glu, Lac
Triglyceride 37.0 mmol/L
BG, pH, K
+
, Ca
2+
, Glu, Lac
Urea
(1)
49.2 mmol/L BG, pH, ISE, Glu, Lac
Uric acid 1.40 mmol/L ISE, Glu, Lac
Vancomycin
(1)
0.069 mmol/L BG, pH, ISE, Glu, Lac
Xylose 4.0 mmol/L BG, pH, ISE, Glu, Lac
(1) The substance and its concentrations are recommended in Clinical and Laboratory Standards Institute.
Interference testing in clinical chemistry, CLSI document EP07-A2; Approved Guideline (2005), Vol.
25, No. 27.
Substance Concentration Tested analyte
Table 6-1 Substances without effect on BG, pH, ISE, Glu, Lac and Hct
Substance Concentration Tested analyte
Beta-carotin
(1)
2.0 mg/L tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Evans blue 5 mg/L tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Gelofusine 1:1 dilution tHb. HHb. O
2
Hb, COHb, MetHb, SO
2
, Bili
HAES-sterile, 10% 1:1 dilution tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Hydroxocobalamin 0.25 mg/mL tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Indocyanine green 5 mg/L tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Intralipid, 20% 10 mg/mL tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Lipidem 10 mg/mL tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Lipofundin, 20% with MCT
(1)
10 mg/mL tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
Methylene blue 2.5 mg/L tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Omegaven
(1)
5 mg/mL tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
, Bili
Patent blue 2.5 mg/L tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
pH high 7.9 tHb, HHb, O
2
Hb, COHb, MetHb, SO
2
pH high 8.0 Bili
Table 6-2 Substances without effect on tHb, SO
2
, Hb derivatives and bilirubin