Roche cobas b 123 User Manual

Roche Diagnostics
Instructions for Use · Version 13.0 145
cobas b 123 POC system 6 Measurement
Interferences
Interferences
A study was carried out to evaluate the influence of chemical substances and
pharmaceuticals that could interfere with measurement parameters.
The study was designed in accordance with the following CLSI guideline:
u Clinical and Laboratory Standards Institute. Interference testing in clinical chemistry,
CLSI document EP07-A2; Approved Guideline (2005), Vol. 25, No. 27
WARNING
Incorrect results due to interference
r Find the list of potential interfering substances for BG/ISE/MSS and COOX parameters
in the tables below:
Substances without effect on BG, pH, ISE, Glu, Lac and Hct
Substance Concentration Tested analyte
3-beta-hydroxybutyric acid 20.0 mmol/L pH, ISE, Glu, Lac
Acetoacetic acid
(1)
2.0 mmol/L pH, ISE, Glu, Lac
Acetone
(1)
12.0 mmol/L BG, pH, ISE, Glu, Lac
Acetylcysteine 10.2 mmol/L
Na
+
, K
+
, Cl
-
, Hct
Albumin > 9%
BG, Na
+
, K
+
, Cl
-
, Glu, Lac, Hct
Ammonium chloride
(1)
0.107 mmol/L BG, pH, ISE, Glu, Lac
Ampicillin
(1)
0.15 mmol/L BG, pH, ISE, Glu, Lac
Ascorbic acid
(1)
0.34 mmol/L ISE, Glu, Lac
Aspirin (acetylsalicylic acid)
(1)
3.62 mmol/L
Na
+
, K
+
, Cl
-
, Glu, Lac
Benzalkonium chloride 0.028 mmol/L
pH, K
+
, Ca
2+
, Cl
-
, Glu, Lac
Bilirubin
(1)
0.342 mmol/L BG, pH, ISE, Glu, Lac
Calcium chloride
(1)
5.0 mmol/L ISE, Glu, Lac
Cefoxitin
(1)
1.546 mmol/L ISE, Glu, Lac
Chlorpromazine
(1)
0.0063 mmol/L BG, pH, ISE, Glu, Lac
Creatinine
(1)
0.442 mmol/L BG, pH, ISE, Glu, Lac
Cyanide 0.1 mmol/L BG, pH, ISE, Glu, Lac
Cyclosporine 0.0043 mmol/L BG, pH, ISE, Glu, Lac
Dobesilate 0.88 mmol/L BG, ISE, Glu, Lac
Dobutamine 0.66 mmol/L
pH, K
+
, Ca
2+
, Cl
-
, Glu, Lac
Dopamine
(1)
0.00587 mmol/L BG, pH, ISE, Glu, Lac
Doxycycline
(1)
0.068 mmol/L BG, pH, ISE, Glu, Lac
EDTA
(1)
0.003 mmol/L ISE, Glu, Lac
Ethanol
(1)
86.8 mmol/L BG, pH
Ethylen glycol
(1)
4.83 mmol/L BG, pH, ISE, Glu, Lac
Gallamine triethiodide 0.056 mmol/L pH, ISE, Glu, Lac
Table 6-1 Substances without effect on BG, pH, ISE, Glu, Lac and Hct

Roche cobas b 123 Specifications

General

Brand	Roche
Model	cobas b 123
Category	Medical Equipment
Language	English