Roche cobas b 123 User Manual

Roche Diagnostics
Instructions for Use · Version 13.0 113
cobas b 123 POC system 4 Theoretical foundations
Calibration principle
Calibration principle
u Calibration (p. 221)
The Fluid Pack contains 3 stable aqueous solutions to calibrate the system’s
parameters.
PO
2
sensor Calibrated using ambient air, corresponding to the oxygen concentration in the
standby solution, and a zero point solution (CAL 2 solution). The oxygen
concentration in the standby solution is calibrated hourly.
PCO
2
, ISE and pH sensors ISE, pH and PCO
2
parameters are calibrated using CAL 2 and standby solutions.
These solutions contain specific electrolyte concentrations, and acidic or basic
components of a pH buffer system. PCO
2
concentration is kept stable because the
calibration solutions in the Fluid Pack are sealed.
Hct Calibrated using conductivity measurements based on an electronic reference point,
and the standby solution, which has a high conductivity.
Glu/Lac sensors Three calibration points are used from CAL 1, CAL 2, and standby solutions.
Oximeter module (tHb, SO
2
, Hb
derivatives, and bilirubin)
Calibrated using a wavelength calibration of the polychromator and a calibration of
the cuvette layer thickness.
Polychromator calibration: The known intensity maxima of the spectral light source
are used as a reference to calibrate the measured signal from the module.
Cuvette layer thickness: The measured absorption of a dye in the CAL 2 solution is
used to calibrate the cuvette layer thickness.

Roche cobas b 123 Specifications

General

Brand	Roche
Model	cobas b 123
Category	Medical Equipment
Language	English