Roche Diagnostics
Instructions for Use · Version 13.0 153
cobas b 123 POC system 6 Measurement
Limitations of clinical analysis
p To measure neonatal bilirubin
1
In the Configuration tab, press the following buttons: Measurement
> Result view > Display.
Make sure that bilirubin is in the Selected values column.
u Configuring the measurement results screen (p. 156)
2
In the Overview tab, measure your sample.
If the bilirubin result is less than 15 mg/dL (256.5 mol/L), the bilirubin result is
displayed.
If the bilirubin result is greater than 15 mg/dL (256.5 mol/L), the plausibility
check is performed.
o If the tHb, and, if Hct is measured, the MCHC results are less than each of
their respective medical decision values (22 g/dL, or 13.64 mmol/L, for tHb
and 36 g/dL, or 5.58 mmol/L, for MCHC), the bilirubin result is displayed.
o If the tHb and/or MCHC results, if Hct is measured, are greater than their
respective medical decision values (22 g/dL, or 13.64 mmol/L, for tHb and 36
g/dL, or 5.58 mmol/L, for MCHC), the bilirubin result is not displayed. If no
result for tHb is available, the bilirubin result is also not displayed.
Figure 6-1 Measurement display screen after a bilirubin measurement fails the
plausibility check
s
Age MCHC (g/dL) MCHC (mmol/L)
1
st
day
31.0–35.0 4.805–5.425
2
nd
to 6
th
day
24.0–36.0 3.720–5.580
7
th
to 13
th
day
n/a n/a
14
th
to 23
rd
day
26.0–34.0 4.030–5.270
24
th
to 37
th
day
25.0–34.0 3.875–5.270
Table 6-5 MCHC reference ranges for neonates
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