30 1100 Series FD Reference Manual
2 First Steps with the Fluorescence Detector
Before You Start
Your normal LC grade solvents usually give good results most of the time. But 
experience shows that baseline noise can be higher (lower signal-to-noise 
ratio) when impurities are in the solvents.
Flush your solvent delivery system for at least 15 minutes before checking 
sensitivity. If your pump has multiple channels, you should also flush the 
channels not in use.