V Series Operating Instructions xxiii
Cautions Introduction
CAUTION: The V 12/V 21 may not meet its performance specifications if stored or 
operated outside of specified temperature and humidity ranges. If 
abnormal performance is observed, additional measures may be 
necessary, such as reorienting or relocating the V 12/V 21.
CAUTION: Do not measure NIBP on patients with sickle-cell disease or on the limb 
where skin damage has occurred or is expected.
CAUTION: Do not use the NIBP cuff on a limb with an intravenous infusion or 
arterial catheter in place. This could cause tissue damage around the 
catheter when the infusion is slowed or blocked during cuff inflation.
CAUTION: Observe caution on all patients (Neonates, Pediatrics, and Adults) when 
NIBP is set to the Stat mode and when using the 1 minute interval. 
When the NIBP Stat is selected, the V 12/V 21 continually takes 
continuous blood pressure readings. As a safety precaution, a limit is 
placed on NIBP Stat mode. In NIBP Stat mode, after 5 minutes or 10 
readings, the NIBP reverts to the previous interval setting. As a safety 
precaution in 1 minute mode, a mandatory 30 second deflation period 
between measurements is added. Reports have been made of nerve 
injury occurring during use of automatically cycled blood pressure 
cuffs
.
CAUTION: To monitor and trend NIBP measurements, the NIBP tile or NIBP list tile 
must be configured to display. No NIBP monitoring occurs unless one of 
these tiles are configured to display. 
CAUTION: When equipped with Nellcor® SpO
2
, use only Nellcor oxygen 
transducers including Nellcor Oxisensor® and OxiMax® patient 
dedicated adhesive sensors. Use of other oxygen transducers may 
cause improper oximeter performance.
CAUTION: When equipped with Masimo SET® SpO
2
, use only Masimo SET Oxygen 
Transducers including Masimo SET LNOP® and LNCS® Patient Dedicated 
Adhesive Sensors and Masimo SET PC Series Patient Cables. Use of 
other oxygen transducers may cause improper oximeter performance.
CAUTION: When a battery has visual signs of damage, or no longer holds a charge, 
it should be replaced. Remove the old battery from the monitor and 
recycle it according to the hospital policy. To dispose of the batteries, 
follow local laws for proper disposal.
CAUTION: Replace Li-Ion batteries with P/N 0146-00-0091-01 ONLY. 
CAUTION: Some pacemakers may contain a respiratory sensor that may produce 
artifact on an ECG waveform.
CAUTION: Tissue damage or inaccurate measurements may be caused by incorrect 
SpO
2 
sensor application or use, such as wrapping too tightly, applying 
supplemental tape, failing to inspect the sensor site periodically, or 
failing to position appropriately. Carefully read the sensor directions 
for use, the V 12/V 21 Operating Instructions, and all precautionary 
information before use.
CAUTION: Inaccurate SpO
2
 measurements may be caused by:
• Incorrect sensor application or use
• Significant levels of dysfunctional hemoglobins, (e.g., 
carboxyhemoglobin or methemoglobin)
• Intra-vascular dyes such as indocyanine green or methylene blue