C-26 624074/07
CASV
®
(Adaptive Support Ventilation)
Figure C-12. Changes of target values in broncho-con-
striction. For clarity, the safety limits are omitted. For clinical
examples, see Belliato 2000.
C.4 Minimum work of breathing (Otis’ equation)
Otis’ basic question was: how do mammals choose their
breathing pattern and on what parameters does it depend
(Otis 1950)? The same question was investigated years before
by Rohrer and a very similar result was obtained (Rohrer 1925).
The hypothesis was that the breath pattern with the least work
of breathing (WOB) is chosen by mammals. Figure C-13 shows
the relationship between rate and WOB graphically, for resis-
tive load, elastic load, and total load to breathing.
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