Gas Measurement Chapter 8 - Monitoring
Apollo Operator’s Manual 119
Part Number: 90 38 237, 6th edition
Age-corrected MAC factors are calculated according
to W.W. Mapleson (British Journal of Anaesthesia
1996, pages 179-185), whose formula only applies
for patients >1 year old:
MAC = MAC 40 x 10
(-0.00269 x (age - 40))
The formula shows the reciprocal relationship
existing between MAC and age.
Age 1 is used for calculation if the age is <1:
Example:
Expiratory concentrations of 0.9 Vol.% isoflurane and
50 Vol.% N
2
O are measured for a 60-year-old
patient.
1 MAC isoflurane at 60 years equals 1.01 according
to the formula above.
1 MAC N
2
O at 60 years equals 92.4 according to the
formula above.
The total MAC factor is calculated as follows:
In other words, 1.4 MAC is obtained with the current
concentration. For a 20-year-old patient, the same
concentration yields a MAC factor of 1.1.
.
Note: The user can configure whether or not the
MAC factor shall be displayed AND whether
or not the MAC factor shall be corrected for
patient age (see page 150 and page 162).
0.9 Vol.% Iso
+
50 Vol.%
N2O
= 1.4
1.01 (MAC Iso) 92.4 (MAC
N2O)
WARNING !
Age-based MAC values only apply if the
patient’s age is greater than or equal to 1 year. If
the patient is younger than 1 year, age-based
MAC for 1 year shall apply.