Rapidlab 1200 Operator’s Guide: System Specifications E-73
02087462 Rev.V
Calibrator Traceability
References
1. International Federation of Clinical Chemistry. Reference method (1986) for
pH measurement in blood. IFCC 1987/3.
2. Clinical and Laboratory Standards Institute. Blood Gas and pH Analysis and
Related Measurements; Approved Guideline; CLSI Document C 46-A; (Vol.
21, No. 14); Sept 2001.
3. Clinical and Laboratory Standards Institute. Standardization of Sodium and
Potassium Ion-Selective Electrode Systems to the Flame Photometric
Reference Method; Approved Standard-Second Edition; CLSI Document
C29 A2; (Vol. 20, No. 17); Oct 2000.
4. Clinical and Laboratory Standards Institute. NRSCL Glucose. CLSI
Document RS1-A; Mar 1989.
5. Clinical and Laboratory Standards Institute. Reference and Selected
Procedures for the Quantitative Determination of Hemoglobin in Blood;
Approved Standard - Third Edition. CLSI Document H15-A3, (Vol. 20,
No. 28); Jan 2000.
Analyte Traceability
pH Traceable to NIST SRM 186 reference material via the IFCC
reference method.
1
pCO
2
and pO
2
Traceable to tonometered aqueous standards prepared using NIST
traceable temperature and pressure standards and gravimetrically
prepared precision gas standards.
Na
+
and K
+
Traceable to NIST SRM 919 or 918 reference materials using flame
photometry
3
or atomic absorption.
Cl
-
Traceable to NIST SRM 919 or 918 reference materials using a
coulometric reference method.
Ca
++
Traceable to gravimetrically prepared internal standards using NIST
SRM 915 and ISE methods embodied in the Siemens systems.
Glucose Traceable to NIST standard reference materials using the hexokinase/
glucose-6-phosphate dehydrogenase method.
4
Lactate Traceable to commercially available standards using a manual
spectrophotometric method.
tHb Traceable to internal standards calibrated against the CLSI
Cyanomethemoglobin Reference Method.
5
FO
2
Hb,
FHHb,
FCOHb,
FMetHb
Spectral properties traceable to NIST gravimetric standards and
verified by assessing tHb versus internal standard calibrated against
the CLSI Cyanomethemoglobin method.