Müse Parameter Descriptions
198
CAEAthena
PN: 905K520652 v2.8
Eyes: Pupil Control
The pupil control parameters are used to control the diameter of the pupils in the eyes. Each eye has
reactive pupils and functional eyelids that blink.
Currently, there are four pupil options that are used to control the diameter of the pupils in both
eyes: Modeled, Reactive, Blown or a Fixed Pupil Size (2 mm to 8 mm).
When the Eyes are set to Reactive, the pupils re-size in response to changes in lighting condition. If
both pupils are set to Reactive, both pupils re-size in a consensual manner.
If the Eyes are set to Modeled, the pupil size is driven by the pharmacology of morphine. In this
mode, the baseline pupil size is 4.7 mm. With increasing effector site concentration of morphine, the
pupils constrict (up to a maximum constriction of 2.8 mm). A dose of 4.6 mg of morphine results in
50% of the maximum effect (a pupil size of 3.75 mm). The reactivity to light is absent for this option
and is only available in the Reactive mode. Presently, when the Modeled option is selected, only
morphine has an effect on pupil size. The pupillary response to other drugs can be made “on the fly”
or scripted using the Scenario Designer.
Other settings allow the user to fix one or both pupils to a specific size.
Default: Reactive
Eyes: Blinking
In Auto mode the eyes are normally blinking. However, the eyes will automatically close under any of
the following conditions:
• SpO2 < 75%
• Spontaneous minute ventilation < 1500 mL
• Neuromuscular blockade (NMB) > 30%
• Non-pulsatile cardiac rhythm
In Auto mode, the eyelids are normally blinking under the following conditions: SpO
2
is greater than
80% systolic blood pressure (SBP) is greater than 70 mmHg and neuromuscular blockade (NMB) is
less than 30%.
The Blinking and Closed settings allow the user to have one or both eyes either blinking or closed
and override the automatic response.
Default: Auto
The Slow, Normal and Fast parameters control the eyelid blinking frequency. Presently, blinking
frequency is not linked to the physiological models. However, the response can be done “on the fly”
or scripted using the Scenario Designer.
Default: Normal
Eyes: Blink Speed
The Blink Speed parameter controls the eyelid blinking frequency and can be set to Slow, Normal,
or Fast. Presently, blinking frequency is not linked to the physiological models. However, the
response can be done “on the fly” or scripted using the Scenario Designer.
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