CAE Athena - Baroreceptor Maximum Pressure; Baroreceptor Minimum Pressure

Müse Parameter Descriptions
226
CAEAthena
PN: 905K520652 v2.8
Baroreceptor Maximum Pressure
Baroreceptor maximum pressure defines the mean arterial pressure (MAP) at which the
baroreceptor inhibitory activity on the heart and systemic vasculature is maximal. When a simulated
patient’s MAP increases above baseline pressure, the baroreceptor response exerts greater inhibitory
controls on the MAP (e.g., reduction in heart rate) in an attempt to return the MAP to the patient’s
baseline pressure. However, these controls have an upper limit, and this “maximum pressure” is
defined as the baroreceptor maximum pressure.
In other words, as the MAP increases, the physiological controls (i.e., baroreceptor response) work to
bring the pressure back toward baseline, primarily by reducing the heart rate. For every 5 mmHg
increase in MAP, the heart rate may decrease by 2 beats per minute in an attempt to keep the MAP in
check. However, there is an upper limit (“maximum pressure”), after which these controls are no
longer effective. Once the MAP reaches the baroreceptor maximum pressure, there is no additional
reduction in heart rate if the pressure continues to rise. For example, should the pressure continue to
rise, the heart rate would not
show a corresponding slowing.
The MAP set-point is exactly between baroreceptor maximum pressure and baroreceptor minimum
pressure.
Default: 112 mmHg
Range: 40 mmHg - 220 mmHg
Baroreceptor Minimum Pressure
Baroreceptor minimum pressure defines the mean arterial pressure (MAP) at which the baroreceptor
inhibitory activity on the heart and systemic vasculature is minimal. When a simulated patient’s MAP
decreases below baseline pressure, the baroreceptor response exerts inhibitory controls on the MAP
(e.g., increase in heart rate) in an attempt to return the MAP to the patient’s baseline pressure.
However, these controls have a lower limit, and this “minimum pressure” is defined as the
baroreceptor minimum pressure.
In other words, as the MAP decreases, the physiological controls (i.e., baroreceptor response) work to
bring the pressure back toward baseline, primarily by increasing the heart rate. For every 5 mmHg
decrease in MAP, the heart rate may increase by 2 beats per minute in an attempt to keep the MAP in
check. However, there is a lower limit (“minimum pressure”), after which these controls are no longer
effective. Once the MAP reaches the baroreceptor minimum pressure, there is no additional increase
in heart rate if the pressure continues to fall. For example, should the pressure continue to fall, the
heart rate would not
show a corresponding increase.
The MAP set-point is exactly between baroreceptor maximum pressure and baroreceptor minimum
pressure.
Default: 72 mmHg
Range: 20 mmHg - 160 mmHg