Müse Parameter Descriptions
210
CAEAthena
PN: 905K520652 v2.8
PetCO
2
- PaCO
2
Factor
The PetCO
2
- PaCO
2
Factor adjusts the end-tidal CO
2
relative to the PaCO
2
. At the default value of 1,
PetCO
2
very closely approximates PaCO
2
. When PetCO
2
- PaCO
2
Factor is set at a value of 2, PetCO
2
is approximately one half of PaCO
2
. PetCO
2
depends on CO
2
production and alveolar ventilation.
Because the alveolar dead space is not modeled physically in the hardware, the responses to
changes in mechanical ventilation settings may not be exact. The use of the Onset feature (e.g., onset
over a 1-minute period) is recommended for this parameter.
Default: 1
Range: 0.9 - 10.0
Respiratory Gain Factor
The Respiratory Gain Factor determines how strong an influence arterial CO
2
levels have on the
simulated patient’s tidal volume and respiratory rate. Under default conditions (value = 1), when
arterial CO
2
levels rise, the patient’s respiratory rate and tidal volume show a transitory increase in an
attempt to return the patient to the physiological control CO
2
set-point. If the Respiratory Gain
Factor is increased to more than 1, the patient has a more pronounced response, while values less
than 1 correspond to a blunted response.
Default: 1
Range: 0.00 - 10.00
Respiratory Quotient
Respiratory Quotient is the rate of carbon dioxide production divided by the rate of oxygen
consumption. Changes to the Respiratory Quotient parameter alter the rate of carbon dioxide
production relative to the rate of oxygen consumption.
Default: 0.8
Range: 0.70 - 1.10
Volume/Rate Control Factor
Ventilatory responses to increased arterial carbon dioxide or decreased arterial oxygen may take the
form of increased tidal volume, increased respiratory rate, or both. The Volume/Rate Control
Factor determines these relative changes. At a value of 1, increased and decreased ventilatory drive
affect tidal volume and respiratory rate equally. When the Volume/Rate Control Factor is greater
than 1, increased or decreased minute ventilation is predominantly achieved by changes in tidal
volume. When the Volume/Rate Control Factor is less than 1, ventilatory changes are affected
primarily by changes in respiratory rate.
For example, set the Volume/Rate Control Factor to 0.1 and increase the shunt fraction to 0.4 to
decrease the arterial O
2
. The patient responds to falling arterial oxygen levels with increased minute
ventilation. Increasing the respiratory rate with minimal increase in tidal volume produces this.
Default: 1
Range: 0.1 - 10.0
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