Müse Parameter Descriptions
212
CAEAthena
PN: 905K520652 v2.8
Lung Compliance Factor: (Left and Right)
These two parameters independently set the left and right lung compliance. Lung Compliance
Factor determines how easily the lungs inflate. Low compliance factors (less than 1) create “stiff”
lungs (such as in acute respiratory distress syndrome or pulmonary edema) requiring more pressure
for expansion. High compliance factors (greater than 1) create “loose” lungs that easily inflate with
less pressure.
Default: 1
Range: 0.15 - 10.00
Venous CO
2
Shift
The Venous CO
2
Shift parameter affects the partial pressure of CO
2
in the venous blood. Changing
this parameter allows large and rapid shifts in total body CO
2
concentration. Increases in alveolar
and arterial CO
2
follow rapidly in a physiologically correct magnitude and time course.
This parameter is useful for giving a “bolus” of CO
2
to the venous system. The alveolar and arterial
CO
2
levels rise rapidly in response to the added carbon dioxide but soon return to “pre-bolus” levels
as increased ventilation efforts work to eliminate the added CO
2
. Therefore, the rise in CO
2
levels is
only transitory. This parameter can be used to simulate external CO
2
administration such as that
used during laparoscopy.
Default: 0 mmHg
Range: 0.0 mmHg - 60.0 mmHg
Bronchial Resistance Factor (Left and Right)
The Bronchial Resistance Factor parameter can be used to set the rate of left and right bronchial
resistance individually. The rate of resistance can also be set to occur over time.
Default: 1
Range: 0.00 - 250,000.00
Alveolar Enflurane
The Alveolar Enflurane parameter is used to simulate the presence of enflurane in the alveolar
space without using real anesthetic vapors. The enflurane percentage is input to the drug models to
achieve the expected pharmacodynamic effects (e.g., respiratory depression).
Using this parameter bypasses pharmacokinetics, real and instructor-specified inspired fractions,
venous content, lung perfusion and ventilation. This parameter can be used to focus on
cardiorespiratory effects (pharmacodynamics).
Note: Müse does not verify a 100 % sum of all fractions, because this would require all fractions to be
set.
Default: Modeled
Range: 0.00% - 5.00%
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